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产品目录

重组大鼠IL-2图片
产品货号:
GS4704
中文名称:
重组大鼠IL-2
英文名称:
Recombinant Rat Interleukin-2
产品规格:
5μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 15.5kDa,a single non-glycosylated polypeptide chain containing 135 amino acids.
储存条件:冷冻(-20℃)

概述

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation.It is expressed by CD4+ and CD8+ T cells,γδ T cells,B cells,dendritic cells,and eosinophils.IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response.The receptor for IL-2 consists of three subunits(55 kDa IL2Rα,75 kDa IL2Rβ,64 kDa common gamma chain γc/IL2Rγ)that are present on the cell surface in varying preformed complexes.Recombinant rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues and it shares about 82%,66%,66%,60%and 54%amino acid sequence identity with mouse,human,rhesus macaque,pig and equus caballus IL-2,respectively.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>97%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.2ng/ml,corresponding to a specific activity of>5.0×106 IU/mg.
成分A 0.2μmfiltered concentrated sterile solution in 10mMsodium citrate,pH 4.0.
内毒素Less than 1 EU/μg of rRtIL-2 as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列APTSSPAKET QQHLEQLLLD LQVLLRGIDN YKNLKLPMML TFKFYLPKQA TELKHLQCLE NELGALQRVL DLTQSKSFHL EDAGNFISNI RVTVVKLKGS ENKFECQFDD EPATVVEFLR RWIAICQSII STMTQ

相关搜索:重组大鼠IL-2IL-2, RatRecombinant Rat Interleukin-2
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